BNFO 301 
Introduction to Bioinformatics
Items for each day generally indicate what is to be done before class
Spring 2010 

January February March April May

Monday
 
Wednesday
   
1: Intro to Molecular Biology
      Read - Belasco et al (1985) +
tour (Part I)
      Problem Set 1 - Intro to Molec Biol
          (focus on B2, B10, C4, C6, D4)
      Questionnaire
      Class cancelled -- Play in the snow!
 
      Please e-mail BioBIKE log by end of Tuesday
  3: Intro to Molecular Biology and Genome Sequencing
      Discussion - Belasco's Differential expression... +
tour (Part II)
      Notes - Overview of genome sequencing
      Notes - Where sequences come from
      Questionnaire
      Problem Set 1 - Intro to Molec Biol
          (focus on B2, B10, C4, C6, D4)
      Lab (if you can make it) - Intro to BioBIKE and Molec Biol
                Tour - Alien genetic code
                Problem Set 2 - Molec Biol Investigations
          Please e-mail in by end of Friday
   
8: Genome Sequencing
    Notes: Where sequences come from
    Retrospective: Belasco et al. (1985) + Tour I and II
    Article: Myers et al. (2000) + Tour
    Questionnaire
    Lab: Sequence Assembly example
            Problem Set 1: Intro to Molec Biol (by experiment)
            Problem Set 2: Molec Biol Investigations (by request)
            Tour: Alien genetic code
  10: Genome Sequencing
    Notes: Where sequences come from
    Article: Myers et al. (2000) + Tour
    Problem Set 2: Molec Biol Investigations
          Please hand in by end of Friday
    Problem Set 3: Genome sequencing
    Questionnaire
    Visual aids: (related to Myers et al and sequencing/assembly)
   
15: Genome Sequencing
    Article: Myers et al. (2000) + Tour
            (especially SQ14 of the tour)
    Discussion: Problem Set 3 (Genome sequencing)
    Questionnaire
    Lab: Problem Set 3 (Genome sequencing)
  17: General problem session
      Questionnaire - What questions to discuss?
      Special Review Session: 10:00 BNFO Computer Lab
      Special Review Session: 11:00 BNFO Computer Lab
      Exam 1 distributed
               What to expect
               Ground rules
   
22: Exam 1 due 8:30 AM
      Post-exam questionnaire
      Genome Analysis (no reading for today)
      Post-mortem: Exam 1
      Lab: Intro to BioBIKE
               Notes: Introduction to mapping
               Notes: Elements of a loop
               Problem Set 4: Practice with loops and mapping
  24: Genome Analysis
      Notes: Search for FMRP in Drosophila
      Notes: Introduction to mapping
      Notes: Elements of a loop
      Post-mortem: Exam 1 (continued)
      Questionnaire
      Group preference survey
                (Please submit by Friday morning)