| Biol 591 |
Course at a Glance : Partial list of topics |
Fall 2002
|
| Scientific Problem | Bioinformatic Tool | |
| 1 | Identification of a possible regulatory site in genomic DNA | Simple simulations, Pattern search programs |
| 2 | Comparison of genomes of pathogenic and nonpathogenic bacteria, looking for genes responsible for pathogenesis | Parsing programs |
| 3 | Alignment of mystery sequence with known anthrax toxins | Sequence alignment |
| 4 | Analysis of a biochemical pathway in order to determine the best site to target a drug | Metabolic modeling |
| 5 | Search for set of genes with common regulation | Position-specific probability matrices |
| 6 | Distinguishing different types of leukemia in order to target treatment | Statistical analysis of microarray data |
| 7 | Identification of genes of foreign origin | Hidden Markov models |
| 8 | Prediction of small molecule that can target receptor of pharmaceutical importance | Molecular modeling |
| 9 | Identification of likely source of emerging pathogen | Phylogenetic analysis |