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Inflammasomes

Zhang C, Boini KM, Xia M, Abais JM, Li X, Liu Q, Li PL . Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia. . Hypertension. 2012 Jul;60(1):154-62.

Abais JM, Zhang C, Xia M, Liu Q, Gehr T, Boini KM, Li PL.NADPH Oxidase-Mediated Triggering of Inflammasome Activation in Mouse Podocytes and Glomeruli during Hyperhomocysteinemia.Antioxid Redox Signal. Epub 2012 Dec 10. 2013 May 1;18(13):1537-48.

Li X, Zhang Y, Xia M, Gulbins E, Boini KM, Li PL. Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis. PLoS One. 2014 Jan 27;9(1):e87552.

Boini KM, Xia M, Abais JM, Li G, Pitzer AL, Gehr TW, Zhang Y, Li PL. Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing. Biochim Biophys Acta. 2014 May;1843(5):836-45.

Xia M, Conley SM, Li G, Li PL, Boini KM. Inhibition of Hyperhomocysteinemia-Induced Inflammasome Activation and Glomerular Sclerosis by NLRP3 Gene Deletion. Cell Physiol Biochem. 2014;34(3):829-41.

Xia M, Boini KM, Abais JM, Xu M, Zhang Y, Li PL. Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin. Am J Pathol. 2014 May;184(5):1617-28.

Abais JM, Xia M, Li G, Chen Y, Conley SM, Gehr TW, Boini KM, Li PL. Nod-like Receptor Protein 3 (NLRP3) Inflammasome Activation and Podocyte Injury via Thioredoxin-Interacting Protein (TXNIP) during Hyperhomocysteinemia. J Biol Chem. 2014 Sep 26;289(39):27159-68.

Abais JM, Xia M, Zhang Y, Boini KM, Li PL.Redox Regulation of NLRP3. Inflammasomes: ROS as Trigger or Effector? Antioxid Redox Signal. 2014 Oct 20. [Epub ahead of print]

Chen Y, Li X, Boini KM, Pitzer AL, Gulbins E, Zhang Y, Li PL. Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis. Biochim Biophys Acta. 2015 Feb;1853(2):396-408.

Zhang Y, Li X, Pitzer AL, Chen Y, Wang L, Li PL. Coronary endothelial dysfunction induced by nucleotide oligomerization domain-like receptor protein with pyrin domain containing 3 inflammasome activation during hypercholesterolemia: beyond inflammation. Antioxid Redox Signal. 2015 May 1;22(13):1084-96.

Li PL. Cardiovascular pathobiology of inflammasomes: inflammatory machinery and beyond. Antioxid Redox Signal. 2015 May 1;22(13):1079-83.

Chen Y, Pitzer AL, Li X, Li PL, Wang L, Zhang Y.Instigation of endothelial Nlrp3 inflammasome by adipokine visfatin promotes inter-endothelial junction disruption: role of HMGB1. J Cell Mol Med. 2015 Aug 20.