Glomerulosclrosis |
Effect of Hyperhomocysteinemia on Plasma or Tissue Adenosine |
Hcys glomerular injury - review |
Hcys glomerular injury Dahl S Rats |
Hcys glomerular redox ceramide |
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Hyperhomocysteinemia associated wiht decrease renal transsul |
Mechanism of Hcy-induced rac1NADPH oxidase actinvation - Vav2 |
| Mechanism of Hcys-induced glomerular injury and Sclerosis - review |
| Podocyte Injury-Hcys |
| Vav2 glomerular sclerosis |
NMDA receptor-mediated activation of NADPH oxidase and glomerulosclerosis in hHcys rats |
Protection of podocytes from hHcys-induced injury by deletion of the gp91phox gene |
Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed HFD |
Acid sphingomyelinase gene deficiency ameliorates the hHcys-induced glomerular injury in mice |
Implication of CD38 gene in podocyte EMT and glomerular sclerosis |
| Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia |
| Acid Sphingomyelinase Gene Knockout Ameliorates Hyperhomocysteinemic Glomerular Injury in Mice Lacking Cystathionine-β-Synthase |
| NADPH Oxidase-Mediated Triggering of Inflammasome Activation in Mouse Podocytes and Glomeruli during Hyperhomocysteinemia |
| Protective role of growth hormone against hyperhomocysteinemia-induced glomerular injury |
| Cross talk between ceramide & redox signaling: implications for endothelial dysfunction and renal disease |
| Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia |
Boini KM, Xia M, Abais JM, Li G, Pitzer AL, Gehr TW, Zhang Y, Li PL. Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing. Biochim Biophys Acta. 2014 May;1843(5):836-45. |
Xia M, Conley SM, Li G, Li PL, Boini KM. Inhibition of Hyperhomocysteinemia-Induced Inflammasome Activation and Glomerular Sclerosis by NLRP3 Gene Deletion. Cell Physiol Biochem. 2014;34(3):829-41. |
Abais JM, Xia M, Li G, Chen Y, Conley SM, Gehr TW, Boini KM, Li PL. Nod-like Receptor Protein 3 (NLRP3) Inflammasome Activation and Podocyte Injury via Thioredoxin-Interacting Protein (TXNIP) during Hyperhomocysteinemia. J Biol Chem. 2014 Sep 26;289(39):27159-68. |
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Abais JM, Xia M, Zhang Y, Boini KM, Li PL.Redox Regulation of NLRP3. Inflammasomes: ROS as Trigger or Effector? Antioxid Redox Signal. 2014 Oct 20. [Epub ahead of print] |
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