Drugs That May Affect or Alter Radiopharmaceutical Distribution in Skeletal Imaging 99mTcMDP or 99mTcHDP
Aluminum carbonate Unexpected organ uptake: liver and kidney)
Aluminum hydroxide Unexpected organ uptake (liver, kidney and increased vascular uptake)
Amphotericin 8 Unexpected organ uptake (liver and genitourinary)
Calcitonin Extraosseous soft tissue uptake
Calcium heparinate Extraosseous soft tissue and muscle uptake
Cimetidine Breast uptake
Cyclophosphamide Intense renal parenchymal/genitourinary uptake
Dialysate Gastric uptake
Doxorubicin Intense renal parenchyma and diffuse myocardium uptake
Estrogen Breast uptake
Ferrous gluconate Decreased skeletal uptake; increased renal and liver uptake
Ferrous sulfate Decreased skeletal uptake; increased renal and liver uptake
Gentamicin Intense renal parenchymal uptake
Heparin (SC) Extraosseous soft tissue uptake
Iodinated contrast media Decreased bone uptake; increased liver uptake
Iron dextran (IM)

Decreased bone uptake and soft tissue uptake

Iron therapy (long term)  
Meperidine (IM) Increased bone, muscle, and soft tissue uptake
Phospo-soda Decreased bone uptake
Potassium phosphate Intense renal, genitourinary and liver uptake
Sodium diatrizoate Decreased bone uptake; increased renal uptake
Steroid therapy (long term) Vincristine

Intense renal parenchymal and genitourinary uptake

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