BNFO 300 
Molecular Biology Through Discovery
Questionnaire on: Jones and Nirenberg (1961) Nature of the Genetic Code
(please press SUBMIT button when finished)
Spring 2016  


I. Basic Information

A. Your name  
II. Old business
  1. Summary of an experiment described in a research article
    Clear on the why, what, and how, of writing a summary?
    How to submit it through the BNFO300 summary blog?


     
  2. Critique of someone else's summary
    Clear on the why and how of writing a critique of a summary?
    How to submit it through the BNFO300 summary blog?


     
  3. Crick et al (1961) and the triplet code
    Regarding the companion to Crick (1961), any concerns about mutagenesis by acridines? Recombination between two phages? The nature of suppressor mutations? How to construct multiply mutant phages? What the double and triple mutants say about the genetic code?
    Issues concerning Problem Set 5, Questions 5 and 6?

     
  4. Research proposal?
    Progress? Problems?

III. Jones & Nirenberg (1962) Survey of RNA codewords

A. How far have you gotten in Jones & Nirenberg (1962) (and its companion)?
The Alien Genetic Code simulation?
     

B. Consider how comfortable you are with the following topics regarding these matters:

  • The overall goal of the work by Nirenberg and others
     
  • The specific focus of Jones & Nirenberg (1961)
     
  • The nature of the experiment
     
  • The nature of RNA produced by polynucleotide phosphorylase
     
  • Theoretical expectations of experiment J108, Table 3
     
  • Interpretation of Table 3
     
  • How in principle to deduce the alien genetic code
     
  • How to use Alien Genetic Code within BioBIKE

IV. Miscellaneous
Any other comments, questions, suggestions, or concerns you may have?
(nb. Issues concerning your proposal are always welcome)

Thanks!

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