am currently interested in studying dependence from cannbinoids and
opioids. So far I have investigated the influence of MAGL and FAAH
inhibition on both cannabinoid and opioid withdrawal, as well as measuring the
potential therapeutic and addictive qualities of substances that modulate
Joel E. Schlosburg, Gracious R. Ross, Rehab A. Abdullah, Steven G. Kinsey, Daniel
K. Nomura, Jonathan Z. Long, Benjamin F. Cravatt, Hamid I. Akbarali, Laura J.
Sim-Selley and Aron H. Lichtman. “Blockade
of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal
symptoms in mice”. JPET;
Ramesh, Joel E. Schlosburg, Jason M. Wiebelhaus and Aron H.
Lichtman. “Marijuana dependence: Not just smoke and mirrors”. ILAR
J; Accepted for publication.
Schlosburg JE, Blankman JL, Pan B,
Nguyen PT, Ramesh D, Kinsey SG, Booker L, Burston JJ, Abdullah RA, Long
JZ, Ghosh S, Wise LE, Selley DE, Sim-Selley LJ, Liu QS, Cravatt BF, &
Lichtman AH. "Sustained inactivation of monoacylglycerol lipase
produces functional antagonism of the brain endocannabinoid system". Nat Neurosci.
2010 Sep; 13(9):1113-9.
Joel E. Schlosburg, Brittany L.A. Carlson, Divya Ramesh, Jonathan Z. Long, Benjamin F. Cravatt and Aron H. Lichtman. “Inhibitors of endocannabinoid metabolizing enzymes reduce precipitated withdrawal responses in THC dependent mice”. AAPS J, 2009 Jun; 11(2):342-52.
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Lichtman, Ph.D. All Rights Reserved.