Behavioral assays and equipment

* = Automated test systems used to reduce variability

Pain & Inflammation

• Acetone-induced cold allodynia test

• Carageenan test

• Cold plate test (allodynia)

• Collagen-induced arthritis model

• Formalin test

• Hargreaves plantar stimulator test (hyperalgesia)

• Hot plate test (analgesia)

• LPS-induced edema model

• Neuropathic pain model (chronic constrictive injury of sciatic nerve)

• Tail flick test (analgesia)

• Tail immersion test (analgesia)

• Visceral pain models

• von Frey test (mechanical allodynia)*

Memory

• Barnes maze*

• Conditioned freezing test* (conditioned fear)

• Morris water maze*

• Passive avoidance*

• Radial arm maze

Depression and anxiety

• Elevated plus maze*

• Light/dark box test*

• Marble burying test*

• Open field test*

• Porsolt forced swim test*

• Tail suspension test*

Locomotor & General activity

• Activity chambers equipped with Anymaze tracking software*

• Infrared home cage activity chambers*

• Open field test*

• Rotarod test*

Evaluation of drug dependence and tolerance

Transgenic & knockout mouse strains

• FAAH (C57BL/6 and DBA1/J background)

• FAAH-NS (Neural tissue-specific FAAH k/o)

• CB1

• CB2

• GPR55

Endocannabinoid quantification via LCMS

Small animal surgical suite

Receptor binding assays

Hormone assays

Cytokine ELISA

Confocal microscopy

Histology core facility

Copyright © 2007-2011  Aron H. Lichtman, Ph.D.  All Rights Reserved.
This page does not reflect an official position of Virginia Commonwealth University.