Our lab works at the interface of materials science, nanotechnology and biology to understand and harness multiscale behavior from the nano to the macro scales.


Openings: Are you interested in Research in Biomedical Devices and/or Biomaterials? Seeking enthusiastic researchers at all levels !



Fall 2023: Our work on elastomeric degradable silk fibroin substrates for bioelectronics published in ACS Applied Bio Materials.



Fall 2023: Our work on a composite of photofibroin and photogelatin published in ACS Biomaterials Science and Engineering. Includes the contribution of a high-school student (Grayson). Some really nice images in this work for cellular applications!



Summer 2023: Our collaborative work with Virginia Tech is published in Micromachines. A novel combination of using deep learning with microscale printing on biomaterials for device security



Summer 2023: Excellent work on silk microneedles by our REU student Kelley Pryor from Hampton University! Thanks for spending your summer with us.



Spring 2023: Delighted to have another excellent DERI student this year. Outstanding work by Grayson !



Spring 2023: Proud of Anne Katherine being awarded the Best Graduate Research Assistant for the College of Engineering for 2022-23. Continuing the tradition of excellence in our lab.


Spring 2023: Anne Katherine presented research at the Annual TERMIS (Boston) and Society for Biomaterials (San Diego) Meetings.



News: Our latest paper in Biosensors & Bioelectronics:X provides a point-of-care detection sensor for cortisol from blood.



Oct 2022:Congrats to Dr. Sayantan Pradhan who presented at the recent VASEM conference on physically unclonable security labels - collaboration with VA Tech and VCU EE.



News: Our recent paper in ACS Applied Bio Materials explores stretchable and electroconductive gelatin biomaterials.

A collaborative effort between a graduate student, undergraduate student and high school DERI student !



News: Congratulations to Jacob for presenting his research at the Chemistry Undergraduate Research Poster Session. Kudos on a Double Major in ChE and Chem and happy trails at RE Mason!!

His research provided insights into soft, flexible and multifunctional hydrogels.



News: Congratulations to Anne Katherine for being awarded the Student Travel Achievement Recognition (STAR) award at the Society for Biomaterials conference 2022!

The prestigious STAR awards recognize research excellence and develop future leaders in Biomaterials Science.


News: Congratulations to Caitlin for her awesome poster at the 14th Annual VCU Poster Symposium for Undergraduate Research and Creativity !

Her research focused on the mechanisms of feed uptake by our favorite worm Bombyx mori



2022: Check out our review on Kirigami-inspired biodesign - co-authored by undergraduate student, graduate student, and postdoc !!
Advanced Materials
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2021: Can squids and silkworms come together? Eumelanin and silk fibroin composites to form bioelectronics ACS Biomaterials Science & Engineering. A collaboration with the 3Bs Institute at the University of Minho, Portugal



News: Proud of group alumni who are now running their own independent labs as Assistant Professors!
Dr. Congzhou Wang @ SDSMT, South Dakota and Dr. Ramendra Pal @ BITS Hyderabad


2021: Flexible and biodegradable temperature sensors using silk lithography is online at ACS Applied Electronic Materials. This article is part of the Forum on Wearable and Biodegradable Sensors.


2020: Our work on kirigami inspired designs for functional silk sheets is online at ACS Applied Materials & Interfaces


2019: Our work on fully integrated organic biosensors is now online in Frontiers in Materials


2019: Our work on making flexible microstructured films using chitin is now online in Journal of Materials Chemistry B


2019: Collaborative work with University of Trento on silk monoliths is now online in Advanced Functional Materials


2019: Our work on flexible biosensors for VEGF detection is now online in ACS Sensors



2019: Our latest paper on Flexible Micropatterned Silk substrates is now online in Advanced Materials Interfaces



2018: Our latest paper on Flexible Biosensors is now online in Biosensors & Bioelectronics


2018: Our recent work on flexible, fully organic, energy storage devices has been published in ACS Applied Materials and Interfaces

US Patent # 9,771,400 has been issued on our work Photoactive silk protein and fabrication of silk protein structures using photolithography

2017: Silk Protein Lithography (SPL) featured as a "Manufacturing Idea to Watch" MFORESIGHT: Alliance for Manufacturing Foresight


Our recent work on Microfabricated Silk-based Flexible Sensors has been published in two papers in Advanced Materials and Biosensors & Bioelectronics

Making Silk Optical Devices with Photolithography featured in C&EN News

Some research projects currently underway:

  • Microfabrication using nanostructured biomaterials
  • Biophysical and biochemical investigations of cell surfaces.
  • Nano and micromechanical characterization of proteins and polymers.
  • Biodiagnostics and cell patterning using microfluidics.


Are you interested in solving some of the "smallest" problems in materials science and engineering?
Contact Dr. Vamsi Yadavalli at vyadavalli [at] vcu.edu for details on specific projects.