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Professor Phone: (804) 827-6264 Fax: (804) 828-0150 |
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Professor Phone: (804) 827-6264 Fax: (804) 828-0150 |
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Antibacterial Drug Development And Antibiotic Resistance
Our current genome-wide essential gene identification provides numerous drug targets for streptococci. We have developed a model to identify essential genes for different bacterial species. Besides S. sanguinis, we have already predicted and confirmed essential genes, using our model, for S. pneumoniae, Streptococcus mutans, Bacillus subtilis and Staphylococcus aureus. These essential genes will become potential targets for antibacterial drug development. Furthermore, as emerging of many antibiotic resistant bacteria recently, the identification of all essential genes in pathogens will provide new strategies to control infective diseases.
Collaborator:
