THE 44th SOUTHEASTERN REGIONAL LIPID CONFERENCE
November 11-13, 2009
High Hampton Inn
Cashiers, NC

Schedule of Events

PLEASE CLICK HERE FOR THE PDF FILE.

Wednesday, November 11, 2009

4:00-6:00pm Registration for all pre-paid SERLC participants: Lobby of High Hampton
5:00-6:00pm

Registrations for all late registration SERLC participants: Lobby of High Hampton

6:00-7:00pm Reception: Wade Hampton Room
7:00-8:00pm Dinner
8:15-8:30pm Opening Remarks by SERLC Chair (Dr. Frank Fang) and Sponsor Recognition: Pavilion
8:30-9:30pm Keynote Speaker: Dr. Jerold Chun, The Scripps Research Institute, San Diego, CA “Lysophospholipid Receptors: From Discovery to Therapy”: Pavilion
9:30pm-midnight Social Time: Wade Hampton Room



Thursday, November 12, 2009


7:00-8:00am

Breakfast
8:00-9:45am

Session I: Lipid Metabolism and Analysis: Pavilion Chair: Dr. JeremyAllegood, Virginia Commonwealth University, Richmond, VA Co-chair:Dr. Guanghu Wang, Medical College of Georgia, Augusta, GA
8:00-8:15am

“Structural diversity and quantitation of sphingomyelins in human plasma” Rebecca Shaner, Georgia Institute of Technology, Atlanta, GA
8:15-8:30am

“Automated surface sampling employing nanoelectrospray mass spectrometry” Jack Henion, Advion BioSystems, Ithaca, NY
8:30-8:45am “S1P export from breast cancer cells by ABCC1 and ABCG2 is stimulated by estradiol” Masayuki Nagahashi, Virginia Commonwealth University, Richmond, VA
8:45-9:00am “Characterization of mice with targeted inactivation of lipid phosphate phosphatase 3 (LPP3) in vascular endothelium” Abdel K. Salous, University of Kentucky, Lexington, KY
9:00-9:15am “Characterization of a lipid kinase involved in the synthesis of alkyl lysophosphatidic Acid” Amanda M. Gellett, University of Virginia, Charlottesville, VA
9:15-9:30am “Adenovirus infection alters metabolism in adipose and hepatic tissues”, Marianna Sukholutsky, Virginia Commonwealth University, Richmond, VA
9:30-9:45am “Multiplexed precursor ion scanning derived glycerophospholipid and fatty acid profiling of liver tissue extracts in patients with non-alcoholic steatohepatitis”,Brigitte Simons, Applied Biosystems|MDS Analytical Technologies, Concord ON, L4K 4V8. Canada
9:45-10:00am Coffee Break
10:00-11:45am:

Session II: Lipid Signaling (focus on glycerolipids and fatty acids): Pavilion
Chair: Dr. Kimberly Paul, Clemson University, Clemson, SC Co-chair: Dr. Paul Baker, University of Pittsburgh School of Medicine, Pittsburgh, PA

10:00-10:15am

“Reactive oxygen species in LPA-dependent signaling pathways”
LeAnn C. Rogers, Wake Forest University School of Medicine, Winston-Salem, NC
10:15-10:30am

“Generation of the bioactive lipid mediator lysophosphatidic acid by Autotaxin/Lysophospholipase D through interaction with platelet integrins”, Zachary Fulkerson, University of Kentucky College of Medicine, Lexington, KY

10:30-10:45am “The role of PLD2/AQP3/PG signaling module in mouse primary keratinocyte proliferation and differentiation”, Haixia Qin, Medical College of Georgia, Augusta, GA
10:45-11:00am “Regulation of pre-mRNA splicing by group VIA phospholipase A2 (iPLA2)”,Bhargavi Emani, Virginia Commonwealth University, Richmond, VA
11:00-11:15am "A dual function phosphatidic acid binding/nuclear localization motif contrls Lipin 1 function in metabolism and adipogenesis", Hongmei Ren, University of Kentucky College of Medicine, Lexington, KY
11:15-11:30am “Activation and translocation of PKCbII in response to pro-differentiative AQP3/PLD2/PG signaling cascade”, Lakiea J. Bailey, Medical College of Georgia, Augusta, GA
11:30-11:45am “Initiation of trypanosoma brucei fatty acid synthesis: functional characterization and localization of acetyl-CoA carboxylase”, Patrick A. Vigueira, Clemson University, Clemson, SC
12:00-1:00pm Lunch
1:00-4:00pm

Free Time (Golfing, hiking, fishing)
4:00-6:00pm Poster Session: Wade Hampton Room
6:00-6:15pm Award Presentations: Pavilion
6:15-7:15pm Keynote Speaker: Dr. William L. Smith, University of Michigan Medical School, Ann Arbor, MI “Allosteric Regulation of Cyclooxygenases by Fatty Acids and Nonsteroidal Anti-inflammatory Drugs”: Pavilion
7:15-8:15pm Dinner
8:30-11:00pm Entertainment: Lobby of High Hampton
11:00pm-Late

Social Time: Wade Hampton Room

Friday, November 13, 2009

7:00-8:00am Breakfast
8:00-9:45am

Session III: Lipid Signaling (focus on sphingolipids): Pavilion
Chair: Dr. Hiroko Hama, Medical University of South Carolina, Charleston, SC
Co-chair, Dr.Kazuaki Takabe, Virginia Commonwealth University, Richmond, VA
8:00-8:15am “Sphingosine kinase 2 and S1P in the nucleus regulate histone acetylation by inhibition of histone deacetylases” Nitai C. Hait, Virginia Commonwealth University School of Medicine, Richmond, VA
8:15-8:30am “Discovery and profile of a sphingosine 1-phosphate (S1P) receptor antagonist pro-drug”, Perry C. Kennedy, University of Virginia, Charlottesville, VA
8:30-8:45am

“Sphingosine-1-phosphate phosphohydrolase 1 at the intersection of ER stress-induced autophagy and apoptosis”, Sandrine Lépine, Virginia Commonwealth University School of Medicine, Richmond, VA
8:45-9:00am “A new ceramide binding site on atypical PKCζ that regulates junction formation in epithelial cells”, Guanghu Wang,Medical College of Georgia, Augusta, GA
9:00-9:15am  “Anti-apoptotic roles of ceramide synthase 6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER stress response pathways”, Can E. Senkal, Medical University of South Carolina, Charleston, SC
9:15-9:30am “Regulation of ultraviolet light-induced ceramide and programmed cell death by ceramide synthase”, Thomas D. Mullen, Medical University of South Carolina, Charleston, SC
9:30-9:45am “Proteolytic processing withinendo-lysosomes is required for maturation of lysosomal acid sphingomyelinase” Russell W. Jenkins, Medical University of South Carolina, Charleston, SC
9:45-10:00am Coffee Break
10:00-11:45am

Session IV: Lipid Pathobiology: Pavilion
Chair: Dr. Ashley Cowart, Medical University of South Carolina, Charleston, SC
Co-chair: Dr. Nadia F. Lamour,
Virginia Commonwealth University School of Medicine, Richmond, VA
10:00-10:15am   

“Anti-apoptotic effects of sphingosine-1 phosphate (S1P) and its analogs on alveolar endothelial and epithelial cells and role in the treatment of emphysema”Krzysztof Kamocki, Indiana University School of Medicine, Indianapolis, IN
10:15-10:30am “Fa2h knockout mice exhibit central nervous system disruption, providing a model of human FA2H deficiency”, Kathleen A. Potter, Medical University of South Carolina, Charleston, SC
10:30-10:45am

“ABC transporter deletion increases PHS tolerance and tryptophan uptake in S. cerevisiae”, Soraya Johnson, University of Iowa,IowaCity, IA
10:45-11:00am

“Modulation of apoptotic cell clearance (efferocytosis) by ceramides”, Daniela N. Petrusca, Indiana University, Indianapolis, IN
11:00-11:15am   

“Bcr-abl dependent regulation of sphingomyelin synthase 1” TaraBurns, Medical University of South Carolina, Charleston, SC
11:15-11:30am “Lipid-induced up-regulation of human acyl-CoA synthetase 5 sensitizes for hepatocellular apoptosis”,Andrea Reinartz, Georgia Institute of Technology, Atlanta, GA
11:30-11:45am “Sphingosine-1-phosphate accelerates the development of functionally mature chymase-expressing human mast cells”, Megan M. Price, Virginia Commonwealth University, School of Medicine, Richmond, VA
11:45-12:00pm Business Meeting
12:00-1:00pm Lunch
1:00pm Departure