Main Page - Deb Labs

Sumitra Deb, Ph.D.

Swati Palit Deb, Ph.D.

Professor of Biochemistry

Contact Information
PO Box 980614
Richmond, VA 23298-0614

Email: sdeb@hsc.vcu.edu
Telephone: 804-827-1375

Research Interests

Publications

Human p53 protein bound to a short DNA fragment. Protein atoms are represented as sticks, the DNA helix is in space filled mode. Click for larger image.

SECTIONS

Associate Professor of Biochemistry

Contact Information

PO Box 980614
Richmond, VA 23298-0614

Email: spdeb@hsc.vcu.edu
Telephone: 804-828-9541

Research Interests

Publications

Recent News and Reports

Recent Publications

p53 Working Group

Molecular Biology of Cell Growth Journal Club

Our lab Members

Related Links

Recent News and Reports

(3/15/05) Recently generated microarray data.

(5/25/05) Website Update (p53 Workgroup and Journal Club page).

(8/26/05) Website Update (Publications, p53 Workgroup and Journal Club page).

(2/14/06) Website Update (Publications, p53 Workgroup and Journal Club page).

(7/16/06) Website Update (Main Page, p53 Workgroup and Journal Club page).

Recent Publications

1. Hetero-oligomerization does not compromise “gain of function” of tumor-derived p53 mutants.

Deb, D., Scian, M., Roth, K.E., Li, W., Keiger, J., Chakraborti, A.S., Deb, S. P. and Deb, S. Oncogene, 21: 176-189, 2002. (Pubmed)

2. Function and dysfunction of the human oncoprotein MDM2.

Deb, S.P. Frontiers in Bioscience. 7:235-243, 2002. (Pubmed)

3. Real –time polymerase chain reaction quantitation of relative expression of genes modulated by p53 using SYBR Green I.

Stagliano, K.E.R., Deb, D., Carchman, E.H, and Deb, S.

Methods in p53 Research; Methods in Molecular Medicine Series, John Walker Eds. Humana Press, USA, 234: 73-91, 2003. (Pubmed)

4. Transactivation and transrepression studies with p53.

Scian, M.J., Frum, R., Deb, S. P., and Deb, S.

Methods in p53 Research; Methods in Molecular Medicine Series, John Walker Eds. Humana Press, USA, 234: 93-110, 2003. (Pubmed)

5. Flow cytometric analysis of MDM2-mediated growth arrest.

Frum, R A. and Deb, S.P.

Methods in p53 Research; Methods in Molecular Medicine Series, John Walker Eds. Humana Press, USA. Vol 234, 257-267, 2003. (Pubmed)

6. Cell Cycle Regulatory Functions of the Human Oncoprotein MDM2.

Deb, S.P. Molecular Cancer Research, 1:1009-1016, 2003. (Pubmed)

7. Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes.

Scian, M., Stagliano, K.E.R., Deb, D., Carchman, E.H., Das, A., Valerie, K., Deb, S.P. and Deb, S. Oncogene, 23: 4430-4443, 2004. (Pubmed)

8. Modulation of gene expression by tumor-derived p53 mutants.

Scian, M.J., Stagliano, K.E.R., Hassan, S., Bowman, M., Miles, M.F., Deb, S.P. and Deb, S. Cancer Res. 2004 Oct 15;64(20):7447-54. (Pubmed)

9. Tumor-derived p53 mutants induce NF-kappaB2 gene expression.

Scian MJ, Stagliano KE, Anderson MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S. Mol Cell Biol. 2005 Nov;25(22):10097-110. (Pubmed)

p53 Working Group

The p53 Working Group is opened to all researchers (including faculty, fellows and students) who are interested in a wide range of research problems relating to p53. The goal of the group is to facilitate both the exchange of ideas and the establishment of collaboration in this research area. The group meets once a month in the Massey Cancer Center’s Conference Room (G120/122). Lunch and refreshments are provided, courtesy of the Massey Cancer Center (RSVP is required).

If you would like to be added to or removed from our mailing list, send an email to sdeb@hsc.vcu.edu.

Please specify, “subscribe” or “unsubscribe” on the subject line.

Molecular Biology of Cell Growth Journal Club

The Journal Club is aimed at bringing together faculty, postdocs and student on various departments whose research focuses on cell biology, cancer biology and development and molecular biology to discuss recent publications of interest. The Journal Club meets twice a month in the Massey Cancer Center’s Conference Room (G120/122). Refreshments are provided, courtesy of the Massey Cancer Center.

Click here for our meeting schedule.

If you would like to be added to or removed from our mailing list, send an email to sdeb@hsc.vcu.edu.

Please specify, “subscribe” or “unsubscribe” on the subject line.

Our Lab Members

Sumitra Deb Lab


Swati Deb Lab
Mahesh Ramamoorthy, M.S.
Lathika Mohanraj, M.S.