GROWTH HORMONE: SYNTHESIS, SECRETION, AND METABOLISM

• ABOUT 1/6 OF THE AP CELLS

• 5 - 10 MG STORED

• 10X ANY OTHER PITUITARY HORMONE

• TWO FORMS 22K AND 20K

• BOUND TO PROTEIN IN BLOOD (SAME COMPOSITION AS RECEPTOR)

• CANNOT ENTER CELL

• DEGRADED IN TARGET CELLS AFTER UPTAKE BY RECEPTOR MEDIATED PROCESS

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