Selected papers on Cancer chemotherapy and tumor growth

White, J.C. and D.C. Mikulecky. Application of Network Thermodynamics to the Computer Modeling of the Pharmacology of Anticancer Agents: A Network Model for Methotrexate Action as a Comprehensive Example, in Membrane Transport of Antineoplastic Agents, I.D. Goldman, ed. Pergamon Press, N.Y. 1986.

Seither, R. L., D. F. Trent, D. C. Mikulecky, T. J. Rape and I. D. Goldman (1989) Folate- Pool Interconversions and Inhibition of Biosynthetic Processes after Exposure of L1210 Leukemia Cells to Antifolates, J. Biol. Chem. 264: 17016-17023.

Seither, R. L., D. Hearne, D. Trent, D. C. Mikulecky and I. D. Goldman (1990) SPICE2 network thermodynamic simulation of antifolate effects on purine and pyrimadine biosynthesis: exploring the role of tetrahydrofolate cofactor depletion versus dihydrofolate feedback inhibition, Computers Math. Applic. 20:87-101.

Seither, R. L., D. F. Trent, D. C. Mikulecky, T. J. Rape and I. D. Goldman (1991) Effect of Direct Suppression of Thymidylate Synthetase at the 5,10-Methylenetetrahydrofolate Binding Site on the Interconversion of Tetrahydrofolate Cofactors to Dihydrofolate by Antifolates, J. Biol. Chem. 266:4112-4118.

Prideaux, J. A., J. L. Ware, A. M. Clarke, and D. C. Mikulecky (1992) From Neural Networks to Cell Signalling: Chemical Communications among Cell Populations, Proc. 14th Ann. Conf. IEEE Eng. Med. Biol. Soc. 64.3-14.

Prideaux, J. A., J. L. Ware, A. M. Clarke, and D. C. Mikulecky (1993) A Modified Neural Network Model of Tumor Cell Interactions and Subpopulation Dynamics, Invasion and Metastisis 13:50-56.

Prideaux, J. A., J. L. Ware, A. M. Clarke, and D. C. Mikulecky (1993) From Neural Networks to Cell Signalling: Chemical Communications in Cell Networks, J. Biol. Sys. 1:131-146.

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