EFFECTS OF GLUCOCORTICOIDS ON ENERGY METABOLISM

• MAINTAIN CARBOHYDRATE RESERVES

• HYPOGLYCEMIA IF ABSENT

• GLUCONEOGENESIS: DIRECT EFFECTS AND INCREASES IN ENZYMES

• DECREASE UTILIZATION OF GLUCOSE BY MUSCLE AND ADIPOSE TISSUE AND LOWER SENSITIVITY TO INSULIN. DIABETES MAY ACCOMPANY CUSHING’S DISEASE WHICH IS A HYPERSECRETION

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