Study Guide I - Radiopharmaceutical Compounding

The goal of this exam is to take an elution of 99mTcO4- and compound radiopharmaceuticals. This is a calculation intensive exam that mimics the preparation of unit doses in a central radiopharmacy. This is also a replication of your homework assignment. Morning elution sheets and Daily Radiopharmaceutical sheets will be provided for the exam. Consider the following:

  1. Calculate the amount of activity in the elution vial and determine its concentration
  2. Measure and calculate your Moly breakthrough (uCi/mCi).
  3. Determine if the Moly breakthrough is acceptable
  4. Prepare/compound a kit
    1. Determine the min/max activity and solution allowed for the kit
    2. Identify the amount of activity needed from the elution vial - consider the amount of doses needed
    3. Identify the amount of saline needed to expand the kit
    4. Identify its concentration in mCi/mL of the radiopharamaceutical
  5. From the compounded radiopharmaceutical
    1. Calculate your unit doses
      1. Adult
      2. Paediatric
    2. Assure that there is enough activity in the compounded radiotracer to dose ALL your patients
  6. Apply the decay formula whenever appropriate
  7. Identity kit expiration and appropriate disposal

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