Drugs That May Affect or Alter Radiopharmaceutical Distribution in Renal Imaging 99mTcDTPA, 99mTcGH, and 9mTcDMSA
Causative Drug Appearance on Scintascan
99mTc pentetrate (DTPA)  
Chlorpromazine Transient decrease in renal plasma flow
Cyclosporine A Nephrotoxicity indistinguishable from ischemic acute tubular necrosis
Darvon compound Decreased renal function
99mTcO4- in stomach/over left kidney Decreased visualization and focal defect (false positive)
Phenacetin-induced interstitial nephritis Unilateral or bilateral decrease s uptake
99mTc gluceptate (GH)  
Acetaminophen Gallbladder uptake and excretion via hepatobiliary system; mimics abnormal kidney localization
Cotrimoxazole Gallbladder uptake end exaction via hepstobiliary system; mimics abnormal kidney localization
99mTcO4- in stomach over left kidney Decreased visualization and focal defect (false positive)
Phenacetin-indcued interstitial nephritis Unilateral or bilateral decrease in uptake
Penicillin G postassium Gallbladder uptake and exaction via hepatobiliary system; mimics abnormal kidney localization
99mTc succimer (DMSA)  
Captopirl (and other Ace inhibitors) Captopril Transient decrease in kidney uptake
99mTcO4- in stomach over left kidney Decreased visualization and focal defect (false positive)
Mannitol Decreased in kidney uptake
Phenacetin-induced interstitial nephritis Unilateral or bilateral decrease in uptake
Sodium bicarbonate Decreased in kidney uptake

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