Imaging infection using ^99mTcMDP and ¹¹¹InWBC

1. Following the injection 25 mCi of ^99mTcMDP pooling images are taken of the feet (see above). The patient has a suspected infection following amputation of several toes
2. 500 uCi of ¹¹¹InWBC was then injected into the patient and delayed images were taken the following day


3. Images are collected using both the ^99mTc peak and ¹¹¹In peak (see above)
4. ROIs are then drawn around the area of interest (see above)
   1. Maximum pixel count in the ^99mTc ROI is 1219
   2. Maximum pixel count in the ¹¹¹In ROI is 602
   3. A ratio is identified (1219/602) as 2.02 which is used for normalization of the indium

      

5. Applying image normalization and summing
1. In order to normalize the indium counts all indium pixel counts are multiplied by 2.02 (see above)
2. ^99mTcMDP images and normalized ¹¹¹InWBC images are summed (see above)
3. Note that there is additional area of focal uptake identified when the images are fused

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