1. Fundamental concepts
   1. How is a prompt event recorded?
      1. LOR
      2. Timing window
      3. Low Energy Threshold
      4. Coincident circuit
      5. PHA
      6. Prompt - Sinogram
   2. Basic concepts behind crystals - why is LYSO better than BGO?
2. TOF
   1. Concept
   2. Calculate
   3. Result - SNR
3. Consider the numerous components that effect resolution
   1. FOV center vs edge
   2. Bed - center vs edge
   3. Radial Elongation
   4. 2 vs 3D
   5. Scatter and Random
   6. 1/3 Beta Max
   7. Non-collinearity
   8. Localization of detectors
   9. Image reconstruction
4. Components that effect contrast
   1. Patient motion
   2. Count density
   3. Tissue density
   4. Noise
   5. Type of lesion
   6. Imaging display
5. PET QC
   1. Normalization
   2. Blank scans
6. Acquisition modes - Where do they apply?
   1. Static - single bed
   2. Whole body
   3. Gated
   4. Dynamic
7. AC of PET/CT
   1. Segmentation
   2. Mono vs poly energetic photons
   3. Scaling
   4. Consider normal and abnormal results when AC correction is applied
8. Discuss the effects of deadtime in a PET scan
   1. Describe the problem
   2. Consider crystal application and how this should reduces the deadtime issue
9. Imaging reconstruction
   1. Compare iterative to FBP
   2. Understand the IR process: OSEM and MLEM

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Part II
10. Clinical PET
    1. Pathophysiology of
       1. ¹⁸FDG
       2. ⁸²RB
       3. ¹⁵O
       4. Na¹⁸F
       5. Review the other radiopharmaceutical used in oncology and compare them to FDG (is there an improvement in detecting disease?)
    2. Oncology
       1. Uptake
       2. The role of PET
          1. Primary tumor and evaluation of metastatic disease
          2. Identifying the surgical candidate (for a and b consider lung cancer)
          3. Application with patients that are on or going to be on chemotherapy
          4. After cancer has been reseeded how can PET be used to assess recurrence of disease
          5. What types of cancer should PET-FDG be used for
       3. PET procedure (general)
          1. Eyes to Thighs
          2. Head to Toe
          3. Single bed (brain)
       4. SUV
          1. Components that must be strictly considered when using SUV assessment in oncology
          2. When the patient has a follow-up exam, what needs to be considered?
    3. Neurology
       1. Know the details on how to complete a PET brain procedure
       2. What concerns are there when imaging the brain with FDG - brain uptake vs. disease vs. white and gray matter
       3. Up/down regulation
       4. Diseases:
          1. Application in Epilepsy
          2. Picks and AD
          3. Assessment with trauma
          4. Low vs high metabolic glioblastoma
    4. Cardiology
       1. Viability with FDG (procedure)
       2. Stress test with ⁸²RB (procedure)
       3. Physiological states of the heart
       4. You do not have to calculate Sr breakthrough, but you should understand the concept

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