| BNFO 300 |
Research Proposals (as of 27 Apr 2017) |
Spring 2017
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Listed below are proposals to be presented May 2017. Each proposal has been justifies and describes a single experiment aimed at addressing a small part of a large and significan question. The aim is depth, getting to the bottom of an experiment to the extent that the presenter can explain the principles behind all techniques used and how the techniques contribute to the experiment. Each proposer has been mentored by a member of the VCU research community.
You can see general advice that was given regarding how to write a research proposal and how to give a presentation. Each presentation will be about 8 minutes.
If you like, you can see what has been done in previous years by going to VCU Review Panel on Molecular Biology Research for the years
2012,
2013,
2014, and
2016 (there was 2015).
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| PROPOSER | MENTOR | TITLE |
| Alina Afzal | Shilpa Ayer | Role of anti-oxidant Vitamin C in mitochondrial DNA mutation of induced pluripotent stem cells (iPSC) |
| Elaf Alaithan | Jamie Sturgill | How does the effect of immunoglobulin on b-cell proliferation cause a generalized immune response to environmental factors in seasonal allergies |
| Wesal Alhammad | Keith Baker | The role of the NR4A orphan nuclear receptors in cardiovascular disease |
| E Alqaffas | Shozo Ozaki | Influenza a, and the process of inhibiting its binding |
| Ashria Arora | Joyce Lloyd | Kruppel-Like Transcription Factor (KPF1) regulates ethrocyte development |
| Amanda Atrash | Javier González-Maeso | Neurotransmitters and the effect they play in expression of DISC1 in the hippocampus region in mice |
| Ruairidh Barlow | Patricia Trimmer | Possible Mutation of NDUFA2 Leads to Parkinson's Disease |
| Erin Cochran | Tricia Smith | Cannabinoid receptor interacting protein 1a (CRIP1a) effect on CB1 inverse agonists |
| Kaivalya Dandamudi | Rita Shiang | Measurement of the p38 signaling pathway in the Pro253Arg mutation of FGFR2 in regulation of bone development in Apert Syndrome |
| Ryan Duong | Greg Walsh | Understanding the involvement of NRAP protein in the dystrophin complex of myocytes |
| Lamis Farah | Darrell Peterson | Folding of HCV envelope protein E2 dependent on HCV envelope protein E1? |
| Josh Fung | Jim Lister | Whether or not juvenile tbx5 cardiomyocytes at the ventricular base are the source of adult cortical layer when antagonized by the tbx5 Dominant Negative |
| Neel Gohil | S Murthy Karnam | Inhibition of enzyme Phospholipase C- Beta1 suppresses the diffusion of Ca 2+ in sarcoplasmic reticulum of smooth muscle cells |
| Lasya Gundlapudi | Jennifer Koblinski | Pathway of trans endothelial leukocyte migration (TEM) through the blood brain barrier |
| Casey Harless | Andrew Eckert? | The role of polyketide synthases in the production of Annonaceous acetogenins |
| Colin Hawkes | Jeff Dupree | Consequences to the axon initial segment after near total removal of microglia in healthy CNS and in mice suffering recent CNS injury |
| Fadi Hijaz | Daniel Conway | Differentially regulated vinculin in cardiomyocytes: Using a Micro-cantilever to study cellular force |
| Deeksha Jain | Tony Faber | Effect of SNP Mutations within MCL-1 on Responsiveness to Chemotherapeutic Measures |
| Jacob Jaminet | Steve Fong | Maltose transportation into S. cerevisiae (yeast) |
| Teja Katravulapalli | Tarynn Witten | |
| EJ Kochis | Shozo Ozaki | Differences in GTPase centers of developmentally regulated rRNAs of Plasmodium |
| Alex Leath | Jeff Elhai | Quantifying tRNA Modifications of an Escherichia coli Strain Post Whole Genome Codon Replacement |
| Kevin Limlengco | Jeff Dupree | Elimination of Microglial Cells in Adult Mice using Cre/Lox Recombinase |
| Amanda Luong | Larisa Litovchick | The transitional mechanisms of the DREAM Complex and the MMB Complex |
| Miral Mahmood | Andrei Ivanov | Anillin overexpression in breast cancer promotes breast cancer migration and metastasis |
| Jared Mann | Amy Adkins, Sean McAllister | Fighting Cancer Stem Cells with natural SOX2 deactivators |
| Diana Marquez | Allison Johnson | Implementing CRISPR Type III-B in human cell to target RNA encoded viruses |
| Tom Mathew | Victoria Stone | How the enzyme m-Ddh leads to periodontitis |
| Rachel Miller | John Ryan | Preventing apoptosis using the relationship between sphingosine 1-phosphate and ceramide |
| Bharath Peddibhotla | Tomek Kordula | How does the aggregation of alpha synuclein prevent mitosphere formation? |
| Aarthi Prakash | Teshell Greene | Improving longevity of Factor IX production using Furin processing |
| Nikhita Puthuveetil | Darrell Peterson | The effects of the duplication of the hairpin structures of the variable region of the 3'UTR of the dengue virus on sfRNA production |
| Danny Rayes | Tony Faber | Structural characteristics of exon 20 insertion mutations in EGFR |
| Thomas Raymond | Glen Kellogg | Design and Synthesis of a Novel APOE Variant for Inhibition of APOE4-Amyloid Beta Binding Complex |
| Jesse Raynor | Glen Kellogg | Comparison of Average Basis Maps of Rotamer Clusters Across All Amino Acids |
| Lucas Rizkalla | Keith Baker | PDK1 Inhibition and Possible Induction of a Mesenchymal-Epithelial Transition as a Curative Measure in Proliferating Cancer Cells |
| Peter Samuel | Jane Roberts | NO Synthase coupled with Arsenic Trioxide as a possible pathway to form free-radicals for apoptosis in GBM cells |
| Ahson Saiyed | Vladimir Vladimirov | |
| Neha Sehgal | Andrew Davies | Over-expression of the Ryanodine Receptor (Unc 68) and the Success of Neuronal Regeneration |
| Ankita Thakur | Stefano Toldo | Treating ischemia and reperfusion injury by reducing the expression of AIM2 in order to restore function of Cardiomyocytes |
| Bethany Yachuw | Gail Christie | Antirepressor identification in Bacillus bacteriophage phiCM3 |