BNFO 300 
Molecular Biology Through Discovery
Questionnaire on notes: Sanger & Tuppy (1951)
(please press SUBMIT button when finished)
Spring 2016  


I. Basic Information

A. Your name 
II. Old business (no need to repeat anything you've said in a previous questionnaire)

A. Problem Set 1 (Part II)
     Anything further you'd like to discuss regarding Problem Set 1?
    

B. Sanger & Tuppy (1953) - Sections I to III
     Anything further you'd like to discuss regarding the article Sanger & Tuppy (1953) and its companion?
     Do you understand what alternative models of protein structure Sanger & Tuppy hoped to distinguish?
     Do you understand how paper chromatography (see presentation) can be used to separate peptides and identify amino acid?
    

III. Sanger & Tuppy (1953)
A. Have you found and downloaded the article Sanger & Tuppy (1953) cited in the companion?
    Are you sure you got the right one? How do you know?
   

B. How far have you gotten in a productive reading of the article?
    You can answer by referring to the last section you read or the last study question you addressed (e.g. SQ12) in the companion.
   

Consider how comfortable you are with the following topics (as defined by the companion to Sanger and Tuppy):

C. The overall strategy Sanger & Tuppy used to determine the sequence of insulin

D. The nature of the figures and tables in the article

E. The differences amongst the various fractions used by Sanger & Tuppy

F. How to interpret Table 3

G. Study questions 4 through 18

With this in mind, how could class time best be spent to meet your needs?
As always, refer to specific matters and relate your current understanding and efforts you've made to address your discomfort.
Do you have any other questions concerning the material in the notes?

IV. Problem Set 1, Problem 1 (community effort)
Have you looked over Problem Set 2, Problem 1 and recognize it as a replay of Sanger & Tuppy (1953)?
Have you looked over the effort to organize the class into groups to answer Problem Set 2, Problem 1?
Do you foresee any problems in accomplishing the task?
V. Miscellaneous
Any other comments, questions, suggestions, or concerns you may have?

Thanks!

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