BNFO 300 
Molecular Biology Through Discovery
Questionnaire on notes: Protein
(please press SUBMIT button when finished)
Fall 2014  


I. Basic Information

A. Your name 
II. Old business (no need to repeat anything you've said in a previous questionnaire)

A. Research Proposal
      What progress have you made in finding a topic/mentor? (The page on How to Find a Mentor) may be helpful to you)
      Can you share ideas that have occured to you regarding a topic? A mentor?
     

B. Wrinch (1936)
      Any final thoughts or concerns regarding Wrinch (1936) in its companion?
      Do you think you have a basic idea what is Wrinch's model of the chromosome?
      Do you see a potential flaw in the model? Consider that
            (a) genes are postulated to exist as micelles of homogeneous fibrous proteins, and
            (b) most proteins must function as enzymes

     

III. Protein structure and function
A. How far have you gotten in the notes entitled Protein?
    You can answer by referring to the last section you read or the last study question you addressed (e.g. SQ12). 

Consider how comfortable you are with the following topics (as defined by the notes Protein):

B. What amino acids are and how they differ from one another

C. How amino acids are joined to form proteins

D. How the sequence of amino acids of a protein contribute to its ultimate three-dimensional shape

E. The distinction between primary, secondary, tertiary, and quaternary structures of proteins

F. How the entire three-dimensional structure participates in forming the critical active site of chymotrypsin

G. Two ways in which hydrophobic amino acids can direct a protein to sit in a membrane

H. How a greater ability to predict protein function from its primary structure would change the world we live in

I. What all of this has to do with bioinformatics

With this in mind, how could class time best be spent to meet your needs?

Choose up to three study questions that you would most like discussed in class:

SQ7  SQ8 SQ9 SQ10 SQ11 SQ12 SQ13 SQ14
IV. Problem Set 3 (Protein Structure)

A. Have you taken a look at any of the problems in this problem set)? (Problems 1, 6, and 4 are of particular interest for Thursday)

B. Do you any issues or concerns come to mind?
     

V. Sanger & Tuppy (1951) (The amino-acid sequence... of insulin)

A. Were you able to find and download this article (and its companion)?

B. Do you foresee any particular problems in using this article to help you grasp how the linear nature of proteins was established?
     

VI. Miscellaneous

Any other comments, questions, suggestions, or concerns you may have?

Thanks!

REMEMBER TO CLICK SUBMIT!