1. Have you found and downloaded the article Perutz et al (1965) cited in the companion?  
    
2. How far have you gotten in the companion to that article? Refer, perhaps, to the last study question you addressed (e.g. SQ12).  
    
3. How far have you gotten in Hemoglobin Structure? Refer, perhaps, to the last section and view you completed (e.g. 4, View 7).  
   (If you are not able to get the tutorial to run, here's a possible solution)
     Consider how comfortable you are with the following topics (as defined by the companion to Perutz et al):
    
4. The different ways protein structures are presented graphically
    
5. The basis for the formation of alpha helices
    
6. The role of hydrophobicity in determining the three dimensional structure of proteins
    
7. How to use Protein Explorer, given help
    
8. The significance of invariant amino acids in the structure of globin
    
9. The significance of prolines in the structure of globin
    
10. With this in mind, how could class time best be spent to meet your needs?
    
    

Choose up to five study questions, those that you have already struggled with, that you would most like discussed in class:

SQ1  SQ2 SQ3 SQ4 SQ5 SQ6 SQ7  SQ8  SQ9 
SQ10 SQ11 SQ12 SQ13 SQ14 SQ15 SQ16 SQ17 
SQ18 SQ19  SQ20 SQ21 SQ22 SQ23 SQ24 SQ25 
SQ26 SQ27 SQ28 SQ29 SQ30 SQ31 SQ32 SQ33 

A. How far have you gotten in the notes DNA Structure?

B. Have you tried your hand at building your own DNA? If so, how did it work out?

Consider how comfortable you are with the following topics (in the notes DNA Structure):

C. The tetranucleotide hypothesis and why if true it would make it impossible for DNA to be the genetic material

D. The Chargaff rules and how they were found

E. How the double slit experiment works

F. How the helical structure of DNA and internucleotide distances can be discerned from Franklin and Gosling's x-ray photograph

G. The biological significance of Watson and Crick's model and how they arrived at it (model building)

Choose up to three study questions related to DNA structure that you would most like discussed in class:

SQ1  SQ2  SQ3  SQ4  SQ5  SQ6  SQ7  SQ8  SQ9 
SQ10  SQ11  SQ12  SQ13 

V. Miscellaneous

Any other comments, questions, suggestions, or concerns you may have?

Thanks!

REMEMBER TO CLICK SUBMIT!