Biol 591 
Introduction to Bioinformatics
Course at a Glance : List of topics
Fall 2003 

 
  Scientific Problem Bioinformatic Tool
1 Comparison of genomes of pathogenic and nonpathogenic bacteria, looking for genes responsible for pathogenesis Parsing programs
2 Identification of a possible regulatory site in genomic DNA Simple simulations, Pattern search programs
3 Alignment of mystery sequence with known anthrax toxins Sequence alignment
4 Analysis of a biochemical pathway in order to determine the best site to target a drug Metabolic modeling
5 Search for set of genes with common regulation Position-specific probability matrices
6 Distinguishing different types of leukemia in order to target treatment Statistical analysis of microarray data
7 Prediction of structure of protein of industrial importance Molecular threading
8 Identification of genes of foreign origin Markov models