Introduction to Bioinformatics - Biol 591

 

SCENARIO
Identification of regulatory sites in genomic DNA
How to avoid being fooled by imposters?

Nitrogen-fixing cyanobacteria: Eat air and prosper!
Certain cyanobacteria, amongst them Nostoc (or Anabaena PCC 7120, are among the only creatures on earth able to survive on CO2 as a source of carbon,  N2 as a source of nitrogen, water as a source of electrons, and sunlight as a source of energy. This is quite a trick, because the process of fixing carbon with electrons from water necessarily produces O2 as a byproduct and the process of fixing N2 is irreversibly inactivated by tiny amounts of oxygen.
Filament of Nostoc. The green cells are photosynthetic vegetative cells. The pale cell is a heterocyst, specialized for nitrogen fixation.
Nostoc is able to protect the machinery of nitrogen-fixation from inactivation by producing specialized cells, called heterocysts, that rigorously exclude oxygen from within them.

This bacterium is therefore a multicellular organism. Each cell contains the same DNA, but different cells express very different sets of genes.

How do they do that? you wonder.

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